KG Hospital did the first ABO-incompatible transplantation or blood group mismatched transplant on 30th September 2014. Human body does not accept even a simple blood transfusion from AB positive person to B positive persion. For Mr. Ganesan, 28 year Goldsmith from ******, Coimbatore after one week of specialized treatment called desensitization, his A positive body was made to accept the mismatched kidney from his AB positive mother. He was discharged after 10 days of hospitalisation hale and healthy.
The boy's 3 year wait for a kidney transplant got finally over. For the last 3 years he was on hemodialysis three times a week and was spending 25,000 rupees every month to keep himself alive and active. Though his father, mother and sister were fit and willing to donate their kidney to him, due to blood group mismatch the kidney transplant was not possible. Patients like Mr. Ganesh who don't find a matched kidney donor in the family normally wait for cadaver or deceased donor transplantation. Due to increasing waiting list for cadaver or deceased donor transplantation, patient's like Mr. Ganesh spend at least 3 Lacs of rupees on dialysis every year. The mortality and morbidity for patients on long term dialysis is very high with 20% patient dying every year and get admitted at least once every year for a major illness.
Thirty percent of all patients are rejected each year due to lack of a blood group matched donor. ABO-incompatible transplantation offers a fresh lease of life to these patients. The long term survival is as good as the regular kidney transplant. And it is cheaper considering the fact that the current waiting time for a cadaver or deceased donor transplantation is at least 3-4 years in Coimbatore. Contrary to the myths, kidney transplant is the best form of treatment for end stage kidney patients. It is not only cost-effective, but also lets the patients live their life to their full potential for the longest possible time. Without transplant, patients end up getting long term dialysis, which is costly (Rs. 3lakhs per annum), affects their quality of life (depend on others and difficult to continue work) and compromise their long term survival (average survival 3-6 years).
KG Hospital is proud that its team of doctors has done such a complex procedure in almost the same cost as a regular kidney transplant and the patient was discharged in a record time. Our Nephrologist, along with his team of doctors, did the first ABO mismatched kidney transplant in the country in April-2009 in CMC, Vellore, and we are happy that the same has been done in KG Hospital also successfully. ABO mismatched transplant is a boon for dialysis dependent patients. For this type of transplantation, unlike most centers, we employ a treatment regimen, which selectively removes the ABO blood group barrier alone without affecting the overall immune system of the patient. Thereby the patients do not have long term side-effects. The long term survival in this new type of transplant is as good as the regular live transplant.
Dr. G. Bakthavathsalam, Chairman of KG Hospital, has been the pillar of support for this venture.