Liver disease is a growing health problem and one of the primary reasons of death worldwide. Hundreds of millions of patients are affected with liver problems globally. Among liver diseases, non alcoholic fatty liver as a severe form of liver disease and is one of the prominent liver diseases worldwide. Under favouring conditions, it might progress into liver cirrhosis and liver cancer, which in its end stage strongly requires organ transplantation. Referable to the scarcity of donor organs, unconventional therapeutic approaches are necessary. Further, the absence of an effective pharmacological therapy for fatty liver is a major motivator for research into new therapeutic approaches for fatty liver. Increased accumulation of fat in liver with subsequent derangements in liver functions is a common finding in patients with excess body fat. Liver failure caused by non-alcoholic fatty liver disease (nafld) is now fetching one of the most common indications for liver transplantation. Fatty liver is a metabolic disease characterized by the incorporation of fat into hepatocytes. Initially, it is a benign condition, but it can progress to hepatitis, an inflammatory disease of the liver that can escort to fibrosis, cirrhosis, or even liver cancer.