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It is immensely ridiculous of digestive systems getting attention only when they muck up. A gala time in gluttony, on a continued basis, shakes the very bases of immune system by disrupting gut flora concentration. It results in a totally embarrassed and naked intestinal tissue vulnerable to pathogens and itâ€™s far from being a cool piece of science. The pathogens dig into the intestinal flesh and make food mix with blood and disrupt the whole show. On the way, they spread to other parts of the body using blood as a vehicle.
But itâ€™s really not your fault if the HLA-DQ (2 & 8) genes left spaces between the intestinal epithelial cells. It is sheer bad luck then.
The Villi and Its Demise:
It takes to understand digestion and its instruments a bit to understand celiac disease, either a genetic or a pathogen-induced disorder. The disease destroys villi (singular: villus), the finger-like projections inside the small intestine that help to digest and absorb nutrition from food by increasing the internal surface area of the intestines. Villi are covered with microvilli, which increases the surface area further. Without the villi, the speed of nutrient absorption would be slow enough to kill a human.
Celiac disease can damage villi and render you unable to get the required nutrition. The villi are destroyed because celiac disease makes the immune system produce antibodies when gluten (protein found in cereals) is present in the stomach. The antibodies attack the gluten attached to the villi taking them as pathogens and the villi are considered a collateral damage. Damage to the small intestineâ€™s lining also opens the doors further for pathogens (in case the disease is genetic) like candida, giardia and protozoans to infect, further complicating the situation.
Celiac Disease: Initial Twists and Turns - Symptoms
Celiac disease; however, isnâ€™t always overt in symptoms, it may chew down tissues elsewhere in the body instead of in within the guts. That includes connective and neural tissues. The nutritional deficiency it creates make people bloat up as dearly as it shrinks them down. Bloating is due to the body sensing saving every bit of nutrition to support a longer survival (this turns metabolism slow); this is when villi are getting destroyed and nutrition absorption turning low.
Find Out If You Have Celiac - Diagnosis
Celiac-s face occasional bouts of stomach pain, gas, diarrhea, extreme fatigue and sudden mood changes too often; they find losing weight as difficult as putting on, may suffer from skin diseases, witness a slowed growth and thin bone structure, less or a huge appetite and many a times, a perpetually rumbling stomach and multiple gastrocolic reflexes a day.
The above are overt symptoms; hidden ones may vary from schizophrenia, ADHD, nervousness and anxiety disorders, frequent urges to throw up, constipation and fibromyalgia. Celiac disease has been found a cause behind intestinal cancers, so both obese and ectomorphs are advised to get done clinical tests for pathogenic infections first. Often, bacteria like giardia or fungi like candida may eat into the mucous membranes and the epithelial cell lining of the intestinal walls, breaking the food/blood barrier. This makes gluten mix directly with blood and the antibodies jump into action.
What if Detected? - Treatment
Giardia is curable with antibiotics but not candida; in fact, antibiotics bring the candida in. They clear out the gut flora royally, making way for the candida. What you need are probiotics and oligosaccharides to go with the antibiotics so that they can occupy the empty grounds before pathogens do.
Next is a dietary change. Discarding gluten will stop the immune responses and give the villi a chance to grow back - unless they have been completely destroyed. This is the time to say goodbye to wheat, rye, barley, malt and oats and welcome fresh animal protein, nuts, seeds, dairy, fruits and vegetables into the diet. There are also herbs and spices that bring great results to fight celiac induced obesity and reverse the disorder (unless a genetic one).